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1

Infectious causes of multiple sclerosis

Gavin Giovannoni, Gary R Cutter, Jan Lunemann, Roland Martin, Christian Münz, Subramaniam Sriram, Israel Steiner, Margaret R Hammerschlag, Charlotte A Gaydos

Journal:

The Lancet Neurology

Year:

2006

Language:

english

File:

PDF, 200 KB

english, 2006

2

Author Correction: Immune reconstitution therapies: concepts for durable remission in multiple sclerosis

Lünemann, Jan D., Ruck, Tobias, Muraro, Paolo A., Bar-Or, Amit, Wiendl, Heinz

Journal:

Nature Reviews Neurology (formerly Nature Clinical Practice Neurology)

Year:

2020

File:

PDF, 290 KB

2020

3

Autophagy-mediated antigen processing in CD4+ T cell tolerance and immunity

Ludger Klein, Christian Münz, Jan D. Lünemann

Journal:

Year:

2010

Language:

english

File:

PDF, 346 KB

english, 2010

4

The initiation and prevention of multiple sclerosis

Ascherio, Alberto, Munger, Kassandra L., Lünemann, Jan D.

Journal:

Nature Reviews Neurology (formerly Nature Clinical Practice Neurology)

Year:

2012

Language:

english

File:

PDF, 428 KB

english, 2012

5

Intravenous immunoglobulin in neurology—mode of action and clinical efficacy

Lünemann, Jan D., Nimmerjahn, Falk, Dalakas, Marinos C.

Journal:

Nature Reviews Neurology (formerly Nature Clinical Practice Neurology)

Year:

2015

Language:

english

File:

PDF, 432 KB

english, 2015

6

Efficacy of Intravenous Immunoglobulin in Neurological Diseases

Lünemann, Jan D., Quast, Isaak, Dalakas, Marinos C.

Journal:

Neurotherapeutics

Year:

2016

Language:

english

File:

PDF, 544 KB

english, 2016

7

Infectious Mononucleosis Triggers Generation of IgG Auto-Antibodies against Native Myelin Oligodendrocyte Glycoprotein

Kakalacheva, Kristina, Regenass, Stephan, Wiesmayr, Silke, Azzi, Tarik, Berger, Christoph, Dale, Russell, Brilot, Fabienne, Münz, Christian, Rostasy, Kevin, Nadal, David, Lünemann, Jan

Journal:

Year:

2016

Language:

english

File:

PDF, 3.78 MB

english, 2016

8

β-Amyloid is a substrate of autophagy in sporadic inclusion body myositis

Jan D. Lünemann, Jens Schmidt, Dorothee Schmid, Konstanze Barthel, Arne Wrede, Marinos C. Dalakas, Christian Münz

Journal:

Annals of Neurology

Year:

2007

Language:

english

File:

PDF, 1.02 MB

english, 2007

9

Intrathymic epstein-barr virus infection is not a prominent feature of myasthenia gravis

Kristina Kakalacheva, Michael A. Maurer, Björn Tackenberg, Christian Münz, Nick Willcox, Jan D. Lünemann

Journal:

Annals of Neurology

Year:

2011

Language:

english

File:

PDF, 418 KB

english, 2011

10

Thalamo-mesencephalic infarction as a single manifestation of combined factor V Leiden and antiphospholipid syndrome

Klaus-Peter Wandinger, Randolf Klingebiel, Jan Dirks Lünemann, Claus Zimmer, Sabine Ziemer, Rolf Zschenderlein

Journal:

Journal of Neurology

Year:

2002

Language:

english

File:

PDF, 261 KB

english, 2002

11

Cross-sectional and longitudinal analysis of myelin-reactive T cells in patients with multiple sclerosis

Jan D. Lünemann*, Sandra Rückert*, Florian Kern, Uwe Wendling, Ruud van der Zee, Hans D. Volk, Frauke Zipp

Journal:

Journal of Neurology

Year:

2004

Language:

english

File:

PDF, 548 KB

english, 2004

12

Isolated abducens nerve paresis associated with high titer of anti-asialo-GM1 followingCampylobacter jejunienteritis

Juri Katchanov, Jan Dirks Lünemann, Florian Masuhr, Andreas Meisel, Helgard Möller, Rolf Zschenderlein

Journal:

Journal of Neurology

Year:

2004

Language:

english

File:

PDF, 131 KB

english, 2004

13

Mechanisms of IVIG Efficacy in Chronic Inflammatory Demyelinating Polyneuropathy

Björn Tackenberg, Falk Nimmerjahn, Jan D. Lünemann

Journal:

Journal of Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 113 KB

english, 2010

14

Epstein-Barr virus and multiple sclerosis

Jan D. Lünemann, Christian Münz

Journal:

Current Neurology and Neuroscience Reports

Year:

2007

Language:

english

File:

PDF, 137 KB

english, 2007

15

Expression and function of the inhibitory Fcγ-receptor in CIDP

Falk Nimmerjahn, Jan D. Lünemann

Journal:

Journal of the Peripheral Nervous System

Year:

2011

Language:

english

File:

PDF, 438 KB

english, 2011

16

Effects of Norepinephrine on Oxygen Consumption of Quiescent and Activated Human Peripheral Blood Mononuclear Cells

JAN D. LÜNEMANN, FRANK BUTTGEREIT, ROBERT TRIPMACHER, CHRISTOPH G.O. BAERWALD, GERD-RÜDIGER BURMESTER, ANDREAS KRAUSE

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 209 KB

english, 2002

17

Antiviral immune responses: triggers of or triggered by autoimmunity?

Münz, Christian, Lünemann, Jan D., Getts, Meghann Teague, Miller, Stephen D.

Journal:

Nature Reviews Immunology

Year:

2009

Language:

english

File:

PDF, 793 KB

english, 2009

18

Norepinephrine Inhibits Energy Metabolism of Human Peripheral Blood Mononuclear Cells via Adrenergic Receptors

Jan D. Lünemann, Frank Buttgereit, Robert Tripmacher, Christoph G. O. Baerwald, Gerd-Rüdiger Burmester, Andreas Krause

Journal:

Bioscience Reports

Year:

2001

Language:

english

File:

PDF, 96 KB

english, 2001

19

Heterogenität von Borrelia burgdorferi: Ätiopathogenetische Relevanz und klinische Implikationen

Jan D. Lünemann, Andreas Krause

Journal:

Zeitschrift für Rheumatologie

Year:

2003

File:

PDF, 114 KB

2003

20

Environmental triggers of multiple sclerosis

Kristina Kakalacheva, Jan D. Lünemann

Journal:

Year:

2011

Language:

english

File:

PDF, 245 KB

english, 2011

21

B cell expression of the inhibitory Fcγ receptor is unchanged in early MS

Manuel Comabella, Xavier Montalban, Kristina Kakalacheva, Deeqa Osman, Falk Nimmerjahn, Mar Tintoré, Jan D. Lünemann

Journal:

Journal of Neuroimmunology

Year:

2010

Language:

english

File:

PDF, 167 KB

english, 2010

22

Elevated Bcl-XL levels correlate with T cell survival in multiple sclerosis

Sonia Waiczies, Alexandra Weber, Jan D. Lünemann, Orhan Aktas, Rolf Zschenderlein, Frauke Zipp

Journal:

Journal of Neuroimmunology

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

23

Viral triggers of multiple sclerosis

Kristina Kakalacheva, Christian Münz, Jan D. Lünemann

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2011

Language:

english

File:

PDF, 582 KB

english, 2011

24

EBV in MS: guilty by association?

Jan D. Lünemann, Christian Münz

Journal:

Trends in Immunology

Year:

2009

Language:

english

File:

PDF, 261 KB

english, 2009

25

TNF-related apoptosis inducing ligand (TRAIL) as a potential response marker for interferon-beta treatment in multiple sclerosis

Klaus-Peter Wandinger, Jan D Lünemann, Oliver Wengert, Judith Bellmann-Strobl, Orhan Aktas, Alexandra Weber, Eva Grundström, Stefan Ehrlich, Klaus-D Wernecke, Hans-Dieter Volk, Frauke Zipp

Journal:

Year:

2003

Language:

english

File:

PDF, 133 KB

english, 2003

26

Elevated Epstein–Barr virus-encoded nuclear antigen-1 immune responses predict conversion to multiple sclerosis

Jan D. Lünemann, Mar Tintoré, Brady Messmer, Till Strowig, Álex Rovira, Héctor Perkal, Estrella Caballero, Christian Münz, Xavier Montalban, Manuel Comabella

Journal:

Annals of Neurology

Year:

2010

Language:

english

File:

PDF, 247 KB

english, 2010

27

The Autoimmune Diseases || Autophagy in Autoimmunity

Year:

2014

Language:

english

File:

PDF, 95 KB

english, 2014

28

TNF-α upregulates macroautophagic processing of APP/β-amyloid in a human rhabdomyosarcoma cell line

Keller, Christian W., Schmitz, Matthias, Münz, Christian, Lünemann, Jan D., Schmidt, Jens

Journal:

Journal of the Neurological Sciences

Year:

2013

Language:

english

File:

PDF, 570 KB

english, 2013

29

Fc Glycan-Modulated Immunoglobulin G Effector Functions

Quast, Isaak, Lünemann, Jan D.

Journal:

Journal of Clinical Immunology

Year:

2014

Language:

english

File:

PDF, 207 KB

english, 2014

30

Targeting dendritic cells to treat multiple sclerosis

Comabella, Manuel, Montalban, Xavier, Münz, Christian, Lünemann, Jan D.

Journal:

Nature Reviews Neurology (formerly Nature Clinical Practice Neurology)

Year:

2010

Language:

english

File:

PDF, 373 KB

english, 2010

31

Progressive change in primary progressive multiple sclerosis normal-appearing white matter: a serial diffusion magnetic resonance imaging study

Schmierer, Klaus, Altmann, Daniel R., Kassim, Nadja, Kitzler, Hagen, Kerskens, Christian M., Doege, Claudia A., Aktas, Orhan, Lünemann, Jan D., Miller, David H., Zipp, Frauke, Villringer, Arno

Journal:

Multiple Sclerosis Journal

Year:

2004

Language:

english

File:

PDF, 782 KB

english, 2004

32

Dual Function of the NK Cell Receptor 2B4 (CD244) in the Regulation of HCV-Specific CD8+ T Cells

Schlaphoff, Verena, Lunemann, Sebastian, Suneetha, Pothakamuri Venkata, Jaroszewicz, Jerzy, Grabowski, Jan, Dietz, Julia, Helfritz, Fabian, Bektas, Hueseyin, Sarrazin, Christoph, Manns, Michael Peter,

Journal:

Year:

2011

Language:

english

File:

PDF, 1.80 MB

english, 2011

33

Borrelia burgdorferi Induces TLR1 and TLR2 in Human Microglia and Peripheral Blood Monocytes but Differentially Regulates HLA-Class II Expression

Cassiani-Ingoni, Riccardo, Cabral, Erik S., Lünemann, Jan D., Garza, Zoila, Magnus, Tim, Gelderblom, Harald, Munson, Peter J., Marques, Adriana, Martin, Roland

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2006

Language:

english

File:

PDF, 782 KB

english, 2006

34

Rituximab induces clonal expansion of IgG memory B-cells in patients with inflammatory central nervous system demyelination

Maurer, Michael A., Tuller, Friederike, Gredler, Viktoria, Berger, Thomas, Lutterotti, Andreas, Lünemann, Jan D., Reindl, Markus

Journal:

Journal of Neuroimmunology

Year:

2016

Language:

english

File:

PDF, 485 KB

english, 2016

35

Macroautophagy as a Pathomechanism in Sporadic Inclusion Body Myositis

Lünemann, Jan D., Schmidt, Jens C., Dalakas, Marinos C., Münz, Christian

Journal:

Year:

2007

Language:

english

File:

PDF, 531 KB

english, 2007

36

Protection from experimental autoimmune encephalomyelitis by polyclonal IgG requires adjuvant-induced inflammation

Quast, Isaak, Keller, Christian W., Weber, Patrick, Schneider, Christoph, von Gunten, Stephan, Lünemann, Jan D.

Journal:

Journal of Neuroinflammation

Year:

2016

Language:

english

File:

PDF, 1.39 MB

english, 2016

37

Regulation of antibody effector functions through IgG Fc N-glycosylation

Quast, Isaak, Peschke, Benjamin, Lünemann, Jan D.

Journal:

Cellular and Molecular Life Sciences

Year:

2017

Language:

english

File:

PDF, 706 KB

english, 2017

38

The third signal cytokine IL-12 rather than immune checkpoint inhibitors contribute to the functional restoration of hepatitis D virus-specific T-cells

Schirdewahn, Thomas, Grabowski, Jan, Sekyere, Solomon Owusu, Bremer, Birgit, Wranke, Anika, Lunemann, Sebastian, Schlaphoff, Verena, Kirschner, Janina, Hardtke, Svenja, Manns, Michael Peter, Cornberg,

Journal:

The Journal of Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 1.27 MB

english, 2016

39

Terminal complement activation is increased and associated with disease severity in CIDP

Quast, Isaak, Keller, Christian W., Hiepe, Falk, Tackenberg, Björn, Lünemann, Jan D.

Journal:

Annals of Clinical and Translational Neurology

Year:

2016

Language:

english

File:

PDF, 297 KB

english, 2016

40

The autophagy machinery restrains iNKT cell activation through CD1D1 internalization

Keller, Christian W., Loi, Monica, Ewert, Svenja, Quast, Isaak, Theiler, Romina, Gannagé, Monique, Münz, Christian, De Libero, Gennaro, Freigang, Stefan, Lünemann, Jan D.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.12 MB

english, 2017

41

Immune and myodegenerative pathomechanisms in inclusion body myositis

Keller, Christian W., Schmidt, Jens, Lünemann, Jan D.

Journal:

Annals of Clinical and Translational Neurology

Year:

2017

Language:

english

File:

PDF, 363 KB

english, 2017

42

Deregulated Fcγ receptor expression in patients with CIDP

Quast, Isaak, Cueni, Flavio, Nimmerjahn, Falk, Tackenberg, Björn, Lünemann, Jan D.

Journal:

Neurology: Neuroimmunology & Neuroinflammation

Year:

2015

Language:

english

File:

PDF, 744 KB

english, 2015

43

ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4 + T cell pathogenicity during CNS inflammation

Keller, Christian W., Sina, Christina, Kotur, Monika B., Ramelli, Giulia, Mundt, Sarah, Quast, Isaak, Ligeon, Laure-Anne, Weber, Patrick, Becher, Burkhard, Münz, Christian, Lünemann, Jan D.

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.36 MB

english, 2017

44

Noncanonical autophagy in dendritic cells triggers CNS autoimmunity

Keller, Christian W., Lünemann, Jan D.

Journal:

Year:

2018

Language:

english

File:

PDF, 558 KB

english, 2018

45

Endocytosis regulation by autophagy proteins in MHC restricted antigen presentation

.Keller, Christian W, Loi, Monica, Ligeon, Laure-Anne, Gannagé, Monique, Lünemann, Jan D, Münz, Christian

Journal:

Current Opinion in Immunology

Year:

2018

Language:

english

File:

PDF, 375 KB

english, 2018

46

Reciprocal Crosstalk between Dendritic Cells and Natural Killer T Cells: Mechanisms and Therapeutic Potential

Keller, Christian W., Freigang, Stefan, Lünemann, Jan D.

Journal:

Frontiers in Immunology

Year:

2017

Language:

english

File:

PDF, 2.75 MB

english, 2017

47

Autophagy and Autophagy-Related Proteins in CNS Autoimmunity

Keller, Christian W., Lünemann, Jan D.

Journal:

Frontiers in Immunology

Year:

2017

Language:

english

File:

PDF, 2.27 MB

english, 2017

48

Fc-Galactosylation of Human Immunoglobulin Gamma Isotypes Improves C1q Binding and Enhances Complement-Dependent Cytotoxicity

Peschke, Benjamin, Keller, Christian W., Weber, Patrick, Quast, Isaak, Lünemann, Jan D.

Journal:

Frontiers in Immunology

Year:

2017

Language:

english

File:

PDF, 3.54 MB

english, 2017

49

IVIG efficacy in CIDP patients is not associated with terminal complement inhibition

Keller, Christian W., Quast, Isaak, Dalakas, Marinos C., Lünemann, Jan D.

Journal:

Journal of Neuroimmunology

Year:

2019

File:

PDF, 276 KB

2019

50

IVIG efficacy in CIDP patients is not associated with terminal complement inhibition

Keller, Christian W., Quast, Isaak, Dalakas, Marinos C., Lünemann, Jan D.

Journal:

Journal of Neuroimmunology

Year:

2019

Language:

english

File:

PDF, 276 KB

english, 2019